CMS Payer Interoperability 2025
24 October 25
| Benjamin Cassity and Maddie Calder
Payer organizations depend on expertise and guidance from their vendor partners to meet continually evolving federal mandates, including the upcoming CMS Interoperability and Prior Authorization Final Rule (CMS-0057-F), which will partially take effect in January 2026. Amid these changes, many payers are reevaluating their interoperability strategies and seeking long-term partners that can not only help them meet CMS mandates but also drive deeper value. This report examines how well vendors deliver CMS interoperability solutions and how well they support customers with proactive guidance; additionally, the report looks at which vendors are top of mind as payers anticipate meeting CMS-0057-F and other mandates.